Recent research has raised significant concerns about the safety of diquat, an herbicide that has been used as an alternative to glyphosate in weed killer products like Roundup. A study published earlier this year highlights the potential health risks associated with diquat, particularly its impact on gut health and various internal organs. As the use of glyphosate declines due to its controversial reputation, diquat’s rising prevalence in agricultural practices warrants a closer examination of its safety profile.
A Closer Look at the Potential Health Risks of Diquat
Diquat is a contact herbicide that has been utilized in agriculture for decades, valued primarily for its effectiveness in controlling weeds in crops such as vineyards and orchards. In light of the controversy surrounding glyphosate, which has faced scrutiny and legal challenges over its alleged carcinogenic properties, diquat is now being marketed as a safer alternative. However, recent research suggests that diquat may pose its own set of serious health risks.
How Does Diquat Work?
Diquat works by damaging plant cell membranes and inducing oxidative stress, a process that evidence suggests can also affect human health. This mechanism of action raises concerns about the herbicide’s potential ability to cause cell and tissue damage in the human body, particularly when exposure occurs through ingestion or skin contact.
Is There a Diquat Ban?
While diquat has been banned in several countries, including the European Union, the United Kingdom, and China, it remains widely used in the United States. The Environmental Protection Agency (EPA) has yet to impose restrictions on diquat, despite growing evidence of its alleged toxicity.
Research Links Diquat Exposure to Gut and Organ Damage
A recent study published in the medical journal Frontiers in Pharmacology indicates that diquat exposure may significantly disrupt gut health and cause organ damage. “From a human health perspective, this stuff is quite a bit nastier than glyphosate so we’re seeing a regrettable substitution, and the ineffective regulatory structure is allowing it,” said Nathan Donley, science director with the Center for Biological Diversity, in a recent interview.
Potential Gut Health Implications
According to research, diquat primarily enters the human body through the digestive tract, which can weaken the intestinal barrier and allow harmful substances to enter the bloodstream, potentially triggering systemic inflammation. This new study warns that diquat can damage gut tissue structure, barrier function, and microbiota after exposure via the digestive tract.
- Impact on Gut Microbiome: Diquat has been linked to a reduction in beneficial gut bacteria, such as Lactobacillus, which play a crucial role in maintaining gut health and overall well-being. The loss of these beneficial microbes can lead to dysbiosis, a condition characterized by an imbalance in the gut microbiome.
- Nutrient Absorption: The damage caused by diquat to the intestinal lining can impair nutrient absorption, leading to deficiencies that may affect overall health.
Possible Damage to Internal Organs
The implications of diquat exposure extend beyond gut health. Research indicates that this herbicide can cause damage to vital organs, including the liver, kidneys, and lungs.
- Kidney Damage: Diquat exposure has been associated with acute kidney injury. The herbicide can allegedly disrupt cellular membranes in the kidneys, leading to inflammation and scarring that may compromise kidney function.
- Liver Dysfunction: The liver is another organ potentially at risk from diquat exposure. Studies suggest that diquat can induce oxidative stress in liver cells, resulting in inflammation and potential long-term damage.
- Respiratory Issues: While diquat is less toxic to the lungs than some other herbicides, it may still trigger inflammation and damage respiratory tissues, raising concerns for individuals with pre-existing lung conditions.
A Call for Stricter Regulations Regarding Diquat
Despite the mounting evidence of diquat’s alleged health risks, regulatory bodies in the United States have been slow to respond. Advocacy groups have called for stricter regulations regarding diquat, arguing that the current oversight is inadequate to protect public health.
Diquat Used in New Roundup Formulation
Bayer, the manufacturer of Roundup weed killer, has reformulated certain Roundup products to replace the original active ingredient, glyphosate, with diquat. The company claims that this change was made to mitigate litigation risks rather than due to safety concerns. However, mounting research suggests that reformulated versions of Roundup may be even more toxic than the glyphosate versions.
Legal Implications and Consumer Awareness
As diquat continues to replace glyphosate in agricultural practices, it is crucial for consumers to remain informed about the potential health risks associated with this herbicide. Ongoing research and regulatory scrutiny are necessary to ensure that public health is prioritized in the face of evolving agricultural practices. Awareness and education are key to making informed decisions about the products we use and their potential impact on our health.
Roundup Lawsuit Information
Roundup Lawsuits, Leading Justice
Effect of Diquat on gut health: molecular mechanisms, toxic effects, and protective strategies, Frontiers in Pharmacology
Weedkiller ingredient widely used in US can damage organs and gut bacteria, research shows, The Guardian
New Study: Reformulated Roundup Potentially More Toxic to Health and Environment, Leading Justice


